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Publications

Dr. Rollin P. Tabuena

Emergence of Candida famata Fungemia in an Immunocompromised Patient: A Case Report Highlighting Clinical Presentation, Diagnosis and Therapeutic Strategy

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Here we report two siblings with ataxia and peripheral neuropathy. One patient showed head tremors.

Ataxia with vitamin E deficiency in the Philippines : A case report of two siblings

The character or timing of chronic cough is considered to be unpredictable for diagnosing its cause. However, the associations of cough triggers with cough pathophysiology remains unknown

Cough Triggers and Their Pathophysiology in Patients with Prolonged or Chronic Cough

This is a case of an adrenal cancer in a 42 year-old female who was admitted because of low back pain and numbness of extremities. During her confinement, she was noted to be hypertensive, hypokalemic with Cushingoid facies.

C-reactive Protein as a Diagnostic Marker for Community Acquired Pneumonia

We report the case of a 60-year-old male with history of surgery for tracheal stenosis 21 years prior to the onset of difficult asthma-like symptoms. Upon exploring the tracheobronchial tree using the fiberoptic bronchoscope, a surgical gauze was found.

An Unusual Iatrogenic Foreign Body (Surgical Gauze) in the Trachea

Pulmonary thromboembolism (PTE) is frequently evaluated in acute care settings. Despite this the clinical diagnosis of PTE is difficult. Results of ventilation-perfusion (V/Q) scans may be inconclusive, pulmonary angiograms (PAGs) are cumbersome, involve risk, and expensive.

The Relationship of D-Dimer Levels With Pulmonary Thromboembolism

Intracerebral hemorrhage (ICH) is more than twice as common as subarachnoid hemorrhage (SAH) and is more likely to result in death or major disability than cerebral infarction or SAH, having an advance age and hypertension are the most important risk factors for ICH.

The Role of Perilesional Edema on the Outcome of Hypertensive Intracerebral Hemorrhage

Objectives To evaluate the usefulness and sensitivity of bronchoalveolar lavage (BAL) as compared to sputum culture for the isolation of specific microorganism among adult patients seen at Iloilo Mission Hospital tertiary hospital in Iloilo City, Philippines. 

Diagnostic Yield Isolate From Bronchoalveolar Lavage Versus Sputum Culture; The Iloilo Mission Hospital Experience

Airway inflammation is considered to be important in asthma but is relatively inaccessible to study. Less invasive methods of obtaining sputum from patients unable to produce it spontaneously should provide a useful investigational tool in asthma.

Use for Eosinophil Count in Induced Sputum and Blood in Evaluating Airway Inflammation In Asthmatic and Normal Subjects; A Prospective Study

Chronic cough, which may be of asthmatic or nonasthmatic origin, is an important clinical issue. Airway inflammation, and remodeling demonstrated by subbasement membrane thickening has been associated with cough variant asthma (CVA) as well as with nonasthmatic chronic cough (NAC). 

Airway Wall Thickening in Patients With Cough Variant Asthma and Nonasthmatic Chronic Cough*

Transient ischemic attack is no longer considered a benign event but rather a critical harbinger of impending stroke. Failure to quickly recognize and evaluate this warning sign could mean missing an opportunity to prevent permanent disability or death.

Cranial CT Scan Findings Among Patients with Transient Ischemic Attack (TIA) at Iloilo Mission Hospital

 Intracerebral hemorrhage (ICH) constitutes 10-15% of all strokes and is associated with poor prognosis. Atherosclerosis is the leading cause of death and disability worldwide. In the USA, there are more than 700,000 stroke victims each year.

C-reactive Protein; Its Prognostic Value in Patients with Acute Hemorrhagic Stroke

Defined as acquired deterioration in cognitive abilities that impairs the successful performance of activities of daily living.

The Mini-Mental Status Examination as a Screening Test for Vascular Dementia Among Chronic Hypertensive patients

As a method that obtains diagnostic samples from a parabronchial or submucosal lesion, the Transbronchial Needle Aspiration (TBNA) uses needles attached to a catheter and is introduced through a rigid or flexible bronchoscope. 

Transbronchial Needle Aspiration (TBNA) Using the Olympus Gauge 21 Cytology Needle in Addition to CDB Versus CDB Alone in the Diagnosis of Submucosal and Peribronchial Lesions

Patients with cough variant asthma, a common cause of chronic cough, may develop wheezing. We examined the determinants of this phenomenon and achievement of remission in 42 patients.

Prognosis of Cough Variant Asthma: A Retrospective Analysis

Peripheral arterial Disease (PAD) due to atherosclerosis is the leading cause of occlusive arterial disease of the extremities and Ankle Brachial Index (ABI) by doppler is used to objectively assess these patients.

Peripheral Arterial Disease's Prevalence Using Ankle Branchial Index (ABI): Its Association to Stroke

Previous studies have shown that there is an association between low BALF (bronchoalveolar lavage fluid) CD4/CD8 ratio and lower remission rates in sarcoidosis patients. To investigate the patient characteristics and clinical features of Japanese sarcoidosis patients with low BALF CD4/CD8 ratios. 

Patient Characteristics and Clinical Features of Japanese Sarcoidosis Patients with Low Bronchoalveolar Lavage CD4 CD8 Ratios

The role of bronchoalveolar lavage fluid (BALF) cell profiles in predicting the clinical outcome of idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP) is still under discussion. To determine whether BALF cell profiles affect the survival of patients with UIP diagnosed by surgical lung biopsy/autopsy at the early stage of IPF. 

Cell Profiles of Bronchoalveolar Lavage Fluid as Prognosticators of Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia among Japanese Patients

One of the major challenges for the clinician in mechanical ventilation is deciding on the best time to wean the patient because 25-30% of patients failed on the initial attempts at discontinuing mechanical ventilation. This accounted for a disproportionate consumption of health care resources.

Weaning Outcome of Neurological Patients at the Intensive Care Unit of West Visayas State University Medical Center

Stroke is one of the leading causes of mortality and its impact in the society is alarming as its sequel may result to disability among surviving patients. Intracerebral hemorrhage, which commonly involves the basal ganglia, is the third most common cause of stroke but is notably devastating form which a fatality rate approaching 50%. 

Prognostic Factors Affecting Mortality of Adult Patients with Hypertensive Hemorrhage of the Basal Ganglia Admitted at West Visayas State University Medical Center

Corticosteroids particularly dexamethasone are known to be effective in reducing vasogenic cerebral edema associated with both primary and metastatic brain tumor or brain abscess. A controversy over the benefit of corticosteroids in treating hypertensive intracerebral hemorrhage (ICH) remains unresolved. 

Effects of Dexamethasone in Hypertensive Intracerebral Hemorrhage of the Basal Ganglia

This case report aimed to describe the outcome of the patient who was diagnosed to have massive middle cerebral infarction that underwent hemicraniectomy which emphasized the value of hemicraniectomy in the management of massive middle cerebral infarction.

Hemicraniectomy in Middle Cerebral Artery Infraction- A Case Report

We report the case of a 60-year-old male with history of surgery for tracheal stenosis 21 years prior to the onset of difficult asthma-like symptoms. Upon exploring the tracheobronchial tree using the fiberoptic bronchoscope, a surgical gauze was found. 

An Unususal Latrogenic Foreign Body Surgical Gauze in the Trachea

Peripheral arterial Disease (PAD) due to atherosclerosis is the leading cause of occlusive arterial disease of the extremities and Ankle Brachial Index (ABI) by doppler is used to objectively assess these patients. 

Peripheral Arterial Disease's Prevalence Using Ankle Branchial Index (ABI): Its Association to Stroke

The balance between matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) may be critical in extracellular matrix remodelling, a characteristic of asthmatic airways.

Relationship of Airway Wall Thickening to an Imbalance Between Matrix Metalloproteinase-9 and Its Inhibitor in Asthma

In the treatment of severe asthma attack, acute application of non-invasive positive pressure ventilation is shown to be beneficial in some selected patients, while endotracheal intubation and mechanical ventilation is required in the remaining cases.

Successful Weaning Using Noninvasive Positive Pressure Ventilation in a Patient with Status Asthmaticus

Four patients with sarcoidosis presented as hypothalamic-hypophyseal syndrome including diabetes insipidus (DI) were followed up for more than 8 years from the onset of clinical manifestation. 

Diabetes Insipidus from Neurosarcoidosis Long Term Follow up For More than Eight Years

The role of bronchoalveolar lavage fluid (BALF) cell profiles in predicting the clinical outcome of idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP) is still under discussion. 

Cell Profiles of Bronchoalveolar Lavage Fluid as Pronosticators of Idiopathic Pulmonary Fibrosis Usual Interstitial Pneumonia Among Japanese Patients

Based on the current multidisciplinary classification of idiopathic interstitial pneumonia (IIP) organized by ATS/ERS, nonspecific interstitial pneumonia (NSIP) is considered as one type of IIP. 

Nonspecific Interstitial Pneumonia: A Real Clinical Entity

An infectious process and malignancy can both present as Solitary Pulmonary Nodule (SPN) dilemma. 

Validation of Bayesian Approach in estimating the probability of malignancy in solitary pulmonary nodules

Based on the current multidisciplinary classification of idiopathic interstitial pneumonia (IIP) organized by ATS/ERS, nonspecific interstitial pneumonia (NSIP) is considered as one type of IIP. 

Nonspecific Interstitial Pneumonia: A Real Clinical Entity

A 59 year-old woman was evaluated because of an elevated carcino-embryonic antigen (CEA). Six years previously, she underwent right upper lobe lobectomy for poorly differentiated adenocarcinoma. 

Metastatic Tumor in the Right Atrium

The increasing incidence of tuberculosis exposes a greater number of patients to the risks of three potentially hepatotoxic drugs, isoniazid, rifamcipin and pyrazinamide. 

Antikoch's Induced Hepatitis - A Veterans Memorial Medical Center Experience

To know the commitment infections after kidney transplantation and to have knowledge on the approach in prevent and treat these infections as an immunocompromised patient.

Cytomegalovirus Pneumonia in Renal Transplant Patient

Based on the current multidisciplinary classification of idiopathic interstitial pneumonia (IIP) organized by ATS/ERS, nonspecific interstitial pneumonia (NSIP) is considered as one type of IIP.

Nonspecific Interstitial Pneumonia: A Real Clinical Entity

To present a case of smoke inhalational injury, its natural course and management Setting: Veterans Memorial Medical Center, a tertiary hospital Case Summary: We are presenting a case of C.M. a 31 year-old female who was admitted to dyspnea.

Smoke Inhalation Injury

Cushing’s syndrome is a condition that results from an excess cortisol, a hormone produced by the adrenal glands. The majority of the case are due to exogenous glucocorticoids.

Cushing's Syndrome from Exogenous Corticosteroids - A Case Series

Ischemic stroke accounts for approximately 85% of all stroke in Europe and North America. Prevention of stroke is a crucial health care issue because it is major cause of disability in developed countries. 

Onset of a Second Stroke in Patients Maintained on Low-dose and Medium-dose Aspirin

There is an increasing awareness that raised plasma fibrinogen is an important predictor of cardiovascular risk and indicator of thrombotic tendency, which can be reduced by anti-platelet therapy. Thrombosis contributes to atherogenesis.

The effect of cilostazol on fibrinogen level in diabetes mellitus type 2 patients with concomitant cardiovascular events and risk factors

 This is a case of an adrenal cancer in a 42 year-old female who was admitted because of low back pain and numbness of extremities. During her confinement, she was noted to be hypertensive, hypokalemic with Cushingoid facies.

Adrenal Carcinoma - A Case Report and Review of Literature

Dr. Ma. Daisy Pedroso-Tabuena

C-reactive Protein; Its Prognostic Value in Patients with Acute Hemorrhagic Stroke

Intracerebral hemorrhage (ICH) constitutes 10-15% of all strokes and is associated with poor prognosis. Atherosclerosis is the leading cause of death and disability worldwide. In the USA, there are more than 700,000 stroke victims each year.

Cranial CT Scan Findings Among Patients with Transient Ischemic Attack (TIA) at Iloilo Mission Hospital

Transient ischemic attack is no longer considered a benign event but rather a critical harbinger of impending stroke. Failure to quickly recognize and evaluate this warning sign could mean missing an opportunity to prevent permanent disability or death.

P08.10 Motor unit number estimate detects motor axon loss much earlier than clinical onset in SOD1 mutation ALS model rats

Article authored by Dr. Daisy Tabuena and Dr. Ryuuji Kaji from Tokushima University.

Application of long-range polymerase chain reaction in the diagnosis of X-Linked Dystonia-Parkinson

X-linked dystonia-parkinsonism (XDP) is a movement disorder endemic to the Philippines.

Onset of a Second Stroke in Patients Maintained on Low-dose and Medium-dose Aspirin

Ischemic stroke accounts for approximately 85% of all stroke in Europe and North America. Prevention of stroke is a crucial health care issue because it is major cause of disability in developed countries.

Effects of Dexamethasone in Hypertensive Intracerebral Hemorrhage of the Basal Ganglia

Corticosteroids particularly dexamethasone are known to be effective in reducing vasogenic cerebral edema associated with both primary and metastatic brain tumor or brain abscess.

Prognostic Factors Affecting Mortality of Adult Patients with Hypertensive Hemorrhage of the Basal Ganglia Admitted at West Visayas State University Medical Center

Stroke is one of the leading causes of mortality and its impact in the society is alarming as its sequel may result to disability among surviving patients.

Hemicraniectomy in Middle Cerebral Artery Infraction- A Case Report

This case report aimed to describe the outcome of the patient who was diagnosed to have massive middle cerebral infarction that underwent hemicraniectomy which emphasized the value of hemicraniectomy in the management of massive middle cerebral infarction. 

Weaning Outcome of Neurological Patients at the Intensive Care Unit of West Visayas State University Medical Center

One of the major challenges for the clinician in mechanical ventilation is deciding on the best time to wean the patient because 25-30% of patients failed on the initial attempts at discontinuing mechanical ventilation.

Peripheral Arterial Disease's Prevalence Using Ankle Branchial Index (ABI): Its Association to Stroke

Peripheral arterial Disease (PAD) due to atherosclerosis is the leading cause of occlusive arterial disease of the extremities and Ankle Brachial Index (ABI) by doppler is used to objectively assess these patients.

Use for Eosinophil Count in Induced Sputum and Blood in Evaluating Airway Inflammation In Asthmatic and Normal Subjects; A Prospective Study

Airway inflammation is considered to be important in asthma but is relatively inaccessible to study. Less invasive methods of obtaining sputum from patients unable to produce it spontaneously should provide a useful investigational tool in asthma.

Peripheral Arterial Disease's Prevalence Using Ankle Branchial Index (ABI): Its Association to Stroke

Peripheral arterial Disease (PAD) due to atherosclerosis is the leading cause of occlusive arterial disease of the extremities and Ankle Brachial Index (ABI) by doppler is used to objectively assess these patients.

Use for Eosinophil Count in Induced Sputum and Blood in Evaluating Airway Inflammation In Asthmatic and Normal Subjects; A Prospective Study

Airway inflammation is considered to be important in asthma but is relatively inaccessible to study. Less invasive methods of obtaining sputum from patients unable to produce it spontaneously should provide a useful investigational tool in asthma. 

C-reactive Protein as a Diagnostic Marker for Community Acquired Pneumonia

This is a case of an adrenal cancer in a 42 year-old female who was admitted because of low back pain and numbness of extremities.

Transbronchial Needle Aspiration (TBNA) Using the Olympus Gauge 21 Cytology Needle in Addition to CDB Versus CDB Alone in the Diagnosis of Submucosal and Peribronchial Lesions

As a method that obtains diagnostic samples from a parabronchial or submucosal lesion, the Transbronchial Needle Aspiration (TBNA) uses needles attached to a catheter and is introduced through a rigid or flexible bronchoscope.

The Mini-Mental Status Examination as a Screening Test for Vascular Dementia Among Chronic Hypertensive patients

To determine the presence of vascular dementia in asymptomatic chronic hypertensive patients unsing the Mini-mental Status Examination (MMSE) and compare the MMSE scores and completion time of chronic hypertensive patients with that of non-hypertensive individuals.

Diagnostic Yield Isolate From Bronchoalveolar Lavage Versus Sputum Culture; The Iloilo Mission Hospital Experience

To evaluate the usefulness and sensitivity of bronchoalveolar lavage (BAL) as compared to sputum culture for the isolation of specific microorganism among adult patients seen at Iloilo Mission Hospital tertiary hospital in Iloilo City, Philippines.

The Role of Perilesional Edema on the Outcome of Hypertensive Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is more than twice as common as subarachnoid hemorrhage (SAH) and is more likely to result in death or major disability than cerebral infarction or SAH, having an advance age and hypertension are the most important risk factors for ICH.

The Relationship of D-Dimer Levels With Pulmonary Thromboembolism

Pulmonary thromboembolism (PTE) is frequently evaluated in acute care settings. Despite this the clinical diagnosis of PTE is difficult.

KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier

Mutations that reduce the function of KCNQ2 channels cause neuronal hyperexcitability, manifested as epileptic seizures and myokymia. These channels are present in nodes of Ranvier in rat brain and nerve and have been proposed to mediate the slow nodal potassium current I(Ks).

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